Never Give Up

The first thing to remember when conducting any job search is never give up. The next thing to remember is never give up. The third to remember...well, you get the idea. You just can't give up.
Easy to say.
Hard to do.
The reason is so important is looking for a job is not a science. It's an art. That means it is best to be creative, do different things and keep at it. It is almost never a matter of "I will do X plus Y and I'll get Z," where Z is a new job.

One last thing to remember - never give up.